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Mannitol
CAS#: 69-65-8
Formula: C6H14O6
M.W.: 182.17
Structural Formula:
Description: Synthesized by sugar with free pyrogen, higher clarity and stability of filtering rate.
Specifications:
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Item
CP2000
BP 2000
USP25
Properties
White crystal powder, odorless, sweet
White crystalline powder, freely soluble in water, very slightly soluble in alcohol, practically insoluble in ether
White crystalline powder, freely soluble in water, very slightly soluble in alcohol, practically insoluble in ether
Melting point, ¡æ
166 -170
165 - 170
164 - 169
Identification
Pass on test
Pass on test
Pass on test
Acidity or alkalinity
¡Ü 0.3ml of 0.02mol/L NaOH
¡Ü 0.3ml of 0.01mol/L HCL or
¡Ü 0.2ml of 0.01mol/L NaOH
¡Ü 0.3ml of 0.02mol/L NaOH
Clarity and colour of a 10%(m/v) solution in water
Clear and colourless
Clear and colourless
-
Chloride, %
¡Ü 0.003
¡Ü 0.005
¡Ü 0.007
Sulphate,%
¡Ü 0.010
¡Ü 0.010
¡Ü 0.01
Oxalate,%
¡Ü 0.020
-
-
Sulphated ash,%
¡Ü 0.1
¡Ü 0.1
-
Loss on dry,%
¡Ü 0.5
¡Ü 0.5
¡Ü 0.3
Arsenic,%
¡Ü 0.0002
-
¡Ü 0.0001
Heavy metal (as Pb),%
¡Ü 0.001
¡Ü 0.00005
-
Nickel,%
-
¡Ü 0.0001
-
Specific rotation
-
+23 ¡ã- +25 ¡ã
(disodium tetraborate solution)
+137 ¡ã-+145 ¡ã
(ammonium molybdate solution)
Reducing sugars
-
-
Not more than a very slight
precipitate is formed
Assay (dried), %
98.0 -102.0
98.0 -101.5
96.0 -101.5
Sorbitol, %
¡¡
¡Ü 2
-
Bacterial endotoxins
-
<100g/l of mannitol, ¡Ü 4 I.U./g
¡Ý 100g/l of mannitol, ¡Ü 2.5 I.U./g
-
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Uses: used in preparing mannitol transfusion and used as drug auxiliary materials, edulcorate of sugarless food.
Packing: 30kg fiber drum, inner lined with PP bags
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